Home Chemistry Heterocyclic Building Blocks Indoles Benzo[Cd]Indol-2(1H)-One
Friedel-Crafts Acylation/Alkylation: Benzo[cd]indol-2(1H)-one can undergo Friedel-Crafts reactions to introduce acyl or alkyl groups onto the aromatic ring using appropriate catalysts and reagents.
Reduction: Reduction of the carbonyl group in benzo[cd]indol-2(1H)-one can be achieved using reducing agents like sodium borohydride or lithium aluminum hydride, leading to the formation of the corresponding alcohol.
Oxidation: You can oxidize the alcohol functionality in benzo[cd]indol-2(1H)-one to form the corresponding carbonyl compound using various oxidizing agents, such as potassium permanganate (KMnO4) or Jones reagent.
Nucleophilic Addition: The carbonyl group in benzo[cd]indol-2(1H)-one can undergo nucleophilic addition reactions with various nucleophiles, such as primary amines, hydrazines, or organometallic reagents, leading to the formation of imine or related compounds.
Cyclization: Depending on the reaction conditions and reagents, benzo[cd]indol-2(1H)-one can participate in intramolecular cyclization reactions to form fused ring systems or other heterocyclic compounds.
Substitution Reactions: The halogen atom at the C-3 position can undergo nucleophilic substitution reactions, such as nucleophilic displacement by a variety of nucleophiles.
Metal-Catalyzed Reactions: Transition metal-catalyzed reactions, such as Suzuki, Heck, or Stille coupling, can be used to introduce aryl or alkyl groups at specific positions in the molecule.
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6-Amino-1-ethylbenzo[cd]indol-2(1H)-one
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1-Butyl-6-chlorobenzo[cd]indol-2(1H)-one
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